Moxifloxacin-warfarin interaction

Two case reports presented here show elevated prothrombin time/international normalized ratios (PT/INR) following coadministration of warfarin and moxifloxacin. Although the underlying mechanism of this interaction still remains unclear, health care providers should be careful when prescribing moxif...

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Detalles Bibliográficos
Autores principales: Ji, Yan, Hokayem, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714043/
https://www.ncbi.nlm.nih.gov/pubmed/23882337
http://dx.doi.org/10.3402/jchimp.v1i4.11512
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author Ji, Yan
Hokayem, Youssef
author_facet Ji, Yan
Hokayem, Youssef
author_sort Ji, Yan
collection PubMed
description Two case reports presented here show elevated prothrombin time/international normalized ratios (PT/INR) following coadministration of warfarin and moxifloxacin. Although the underlying mechanism of this interaction still remains unclear, health care providers should be careful when prescribing moxifloxacin to patients on warfarin therapy, especially to patients with low albumin levels. More frequent monitoring of INR in these patients may be warranted.
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spelling pubmed-37140432013-07-23 Moxifloxacin-warfarin interaction Ji, Yan Hokayem, Youssef J Community Hosp Intern Med Perspect Case Report Two case reports presented here show elevated prothrombin time/international normalized ratios (PT/INR) following coadministration of warfarin and moxifloxacin. Although the underlying mechanism of this interaction still remains unclear, health care providers should be careful when prescribing moxifloxacin to patients on warfarin therapy, especially to patients with low albumin levels. More frequent monitoring of INR in these patients may be warranted. Co-Action Publishing 2012-01-26 /pmc/articles/PMC3714043/ /pubmed/23882337 http://dx.doi.org/10.3402/jchimp.v1i4.11512 Text en © 2011 Yan Ji and Youssef Hokayem http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ji, Yan
Hokayem, Youssef
Moxifloxacin-warfarin interaction
title Moxifloxacin-warfarin interaction
title_full Moxifloxacin-warfarin interaction
title_fullStr Moxifloxacin-warfarin interaction
title_full_unstemmed Moxifloxacin-warfarin interaction
title_short Moxifloxacin-warfarin interaction
title_sort moxifloxacin-warfarin interaction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714043/
https://www.ncbi.nlm.nih.gov/pubmed/23882337
http://dx.doi.org/10.3402/jchimp.v1i4.11512
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