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A Study of Potential Pharmacokinetic and Pharmacodynamic Interactions between Dextromethorphan/Quinidine and Memantine in Healthy Volunteers

Background and Objective: Dextromethorphan/quinidine (DMQ) is the first agent indicated for the treatment of pseudobulbar affect. Dextromethorphan, the active ingredient, is a low-affinity, uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. This study evaluated the potential for a drug-d...

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Detalles Bibliográficos
Autores principales:	Pope, Laura E., Schoedel, Kerri A., Bartlett, Cynthia, Sellers, Edward M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2012
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714141/ https://www.ncbi.nlm.nih.gov/pubmed/22712629 http://dx.doi.org/10.1007/BF03261905

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