Cargando…

Serial MR diffusion to predict treatment response in high-grade pediatric brain tumors: a comparison of regional and voxel-based diffusion change metrics

BACKGROUND: Assessment of treatment response by measuring tumor size is known to be a late and potentially confounded response index. Serial diffusion MRI has shown potential for allowing earlier and possibly more reliable response assessment in adult patients, with limited experience in clinical se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodriguez Gutierrez, Daniel, Manita, Muftah, Jaspan, Tim, Dineen, Robert A., Grundy, Richard G., Auer, Dorothee P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714149/ https://www.ncbi.nlm.nih.gov/pubmed/23585630 http://dx.doi.org/10.1093/neuonc/not034

Ejemplares similares

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients
por: Izquierdo, Elisa, et al.
Publicado: (2021)

Glucose transporter Glut1 controls diffuse invasion phenotype with perineuronal satellitosis in diffuse glioma microenvironment
por: Miyai, Masafumi, et al.
Publicado: (2020)

Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma
por: du Chatinier, Aimée, et al.
Publicado: (2022)

Early-onset grade 2-3 diffuse gliomas and schwannomas increase the risk of central nervous system tumors among the patients’ relatives
por: Alanen, Eljas, et al.
Publicado: (2023)

MR-guided focused ultrasound increases antibody delivery to nonenhancing high-grade glioma
por: Brighi, Caterina, et al.
Publicado: (2020)

Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors
por: Kashani, Elham, et al.
Publicado: (2022)

Inhibition of microglial EZH2 leads to anti-tumoral effects in pediatric diffuse midline gliomas
por: Keane, Lily, et al.
Publicado: (2021)

Spatial concordance of DNA methylation classification in diffuse glioma
por: Verburg, Niels, et al.
Publicado: (2021)

Receptor-driven invasion profiles in diffuse intrinsic pontine glioma
por: Karki, Anju, et al.
Publicado: (2021)

Tumor-related molecular determinants of neurocognitive deficits in patients with diffuse glioma
por: van Kessel, Emma, et al.
Publicado: (2022)

Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma
por: Messinger, Dana, et al.
Publicado: (2022)

Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas
por: Granberg, Kirsi J, et al.
Publicado: (2017)

Predicting methylation class from diffusely infiltrating adult gliomas using multimodality MRI data
por: Alom, Zahangir, et al.
Publicado: (2023)

Frequency of false-positive FISH 1p/19q codeletion in adult diffuse astrocytic gliomas
por: Ball, Matthew K, et al.
Publicado: (2020)

HER2 chimeric antigen receptor T cell immunotherapy is an effective treatment for diffuse intrinsic pontine glioma
por: Wang, Stacie S, et al.
Publicado: (2023)

Descriptive and retrospective analysis of diffuse glioma patients with symptomatic SARS-CoV2 infection during the first wave of the pandemic
por: Lozano-Sanchez, Fernando, et al.
Publicado: (2021)

An EZH2 blocker sensitizes histone mutated diffuse midline glioma to cholesterol metabolism inhibitors through an off-target effect
por: Rahal, Farah, et al.
Publicado: (2022)

STAT3 is a biologically relevant therapeutic target in H3K27M-mutant diffuse midline glioma
por: Zhang, Liang, et al.
Publicado: (2022)

Overcoming translational barriers in H3K27-altered diffuse midline glioma: Increasing the drug-tumor residence time
por: Power, Erica A, et al.
Publicado: (2023)

High-throughput microRNA profiling of pediatric high-grade gliomas
por: Miele, Evelina, et al.
Publicado: (2014)

An affinity for brainstem microglia in pediatric high-grade gliomas of brainstem origin
por: Zats, Liat Peretz, et al.
Publicado: (2022)

Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma
por: Duchatel, Ryan J, et al.
Publicado: (2021)

Leptomeningeal disease and tumor dissemination in a murine diffuse intrinsic pontine glioma model: implications for the study of the tumor-cerebrospinal fluid-ependymal microenvironment
por: Pan, Shelei, et al.
Publicado: (2022)

MRI-guided focused ultrasound blood–brain barrier opening increases drug delivery and efficacy in a diffuse midline glioma mouse model
por: Martinez, Payton, et al.
Publicado: (2023)

Multicellular “hotspots” harbor high-grade potential in lower-grade gliomas
por: Kirby, Alastair J, et al.
Publicado: (2021)

Pediatric high-grade gliomas and the WHO CNS Tumor Classification—Perspectives of pediatric neuro-oncologists and neuropathologists in light of recent updates
por: Gielen, Gerrit H, et al.
Publicado: (2022)

The natural compound obtusaquinone targets pediatric high-grade gliomas through ROS-mediated ER stress
por: Teng, Jian, et al.
Publicado: (2020)

Transitioning to molecular diagnostics in pediatric high-grade glioma: experiences with the 2016 WHO classification of CNS tumors
por: Baugh, Joshua N, et al.
Publicado: (2021)

MR1 overexpression correlates with poor clinical prognosis in glioma patients
por: Kubica, Phillip, et al.
Publicado: (2021)

Integrative molecular characterization of pediatric spinal ependymoma: the UK Children’s Cancer and Leukaemia Group study
por: Ahmad, Omar, et al.
Publicado: (2021)

Establishment of patient-derived organoid models of lower-grade glioma
por: Abdullah, Kalil G, et al.
Publicado: (2021)

Molecular subgrouping of medulloblastoma based on few-shot learning of multitasking using conventional MR images: a retrospective multicenter study
por: Chen, Xi, et al.
Publicado: (2020)

Parents’ experiences of postmortem tumor donation for high-grade gliomas: benefits and suggested improvements
por: Robertson, Eden G, et al.
Publicado: (2021)

Combined molecular subtyping, grading, and segmentation of glioma using multi-task deep learning
por: van der Voort, Sebastian R, et al.
Publicado: (2022)

IDH mutation status is associated with distinct vascular gene expression signatures in lower-grade gliomas
por: Zhang, Lei, et al.
Publicado: (2018)

Structural gray matter alterations in glioblastoma and high-grade glioma—A potential biomarker of survival
por: Lamichhane, Bidhan, et al.
Publicado: (2023)

Outcomes after combined use of intraoperative MRI and 5-aminolevulinic acid in high-grade glioma surgery
por: Schatlo, Bawarjan, et al.
Publicado: (2015)

Optimization of deep learning methods for visualization of tumor heterogeneity and brain tumor grading through digital pathology
por: Truong, An Hoai, et al.
Publicado: (2020)

Tumor mutational burden predicts survival in patients with low-grade gliomas expressing mutated IDH1
por: Alghamri, Mahmoud S, et al.
Publicado: (2020)

Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion
por: Hussein, Deema, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_u4csc17ndgbocto3893g4ud0q7