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Distinct Pools of Non-Glycolytic Substrates Differentiate Brain Regions and Prime Region-Specific Responses of Mitochondria
Many hereditary diseases are characterized by region-specific toxicity, despite the fact that disease-linked proteins are generally ubiquitously expressed. The underlying basis of the region-specific vulnerability remains enigmatic. Here, we evaluate the fundamental features of mitochondrial and glu...
Autores principales: | Lee, Do Yup, Xun, Zhiyin, Platt, Virginia, Budworth, Helen, Canaria, Christie A., McMurray, Cynthia T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714274/ https://www.ncbi.nlm.nih.gov/pubmed/23874783 http://dx.doi.org/10.1371/journal.pone.0068831 |
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