Cargando…

Circulating Lysophosphatidylcholines Are Markers of a Metabolically Benign Nonalcoholic Fatty Liver

OBJECTIVE: Nonalcoholic fatty liver (NAFL) is thought to contribute to insulin resistance and its metabolic complications. However, some individuals with NAFL remain insulin sensitive. Mechanisms involved in the susceptibility to develop insulin resistance in humans with NAFL are largely unknown. We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lehmann, Rainer, Franken, Holger, Dammeier, Sascha, Rosenbaum, Lars, Kantartzis, Konstantinos, Peter, Andreas, Zell, Andreas, Adam, Patrick, Li, Jia, Xu, Guowang, Königsrainer, Alfred, Machann, Jürgen, Schick, Fritz, Hrabé de Angelis, Martin, Schwab, Matthias, Staiger, Harald, Schleicher, Erwin, Gastaldelli, Amalia, Fritsche, Andreas, Häring, Hans-Ulrich, Stefan, Norbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714475/ https://www.ncbi.nlm.nih.gov/pubmed/23514731 http://dx.doi.org/10.2337/dc12-1760

Ejemplares similares

Relationships of Circulating Sex Hormone–Binding Globulin With Metabolic Traits in Humans
por: Peter, Andreas, et al.
Publicado: (2010)

Circulating Palmitoleate Strongly and Independently Predicts Insulin Sensitivity in Humans
por: Stefan, Norbert, et al.
Publicado: (2010)

Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene
por: Kantartzis, Konstantinos, et al.
Publicado: (2009)

Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content
por: Machicao, Fausto, et al.
Publicado: (2016)

Cholesterol Synthesis Is Associated with Hepatic Lipid Content and Dependent on Fructose/Glucose Intake in Healthy Humans
por: Silbernagel, Guenther, et al.
Publicado: (2012)

Individual Stearoyl-CoA Desaturase 1 Expression Modulates Endoplasmic Reticulum Stress and Inflammation in Human Myotubes and Is Associated With Skeletal Muscle Lipid Storage and Insulin Sensitivity In Vivo
por: Peter, Andreas, et al.
Publicado: (2009)

Common Genetic Variation in the Human FNDC5 Locus, Encoding the Novel Muscle-Derived ‘Browning’ Factor Irisin, Determines Insulin Sensitivity
por: Staiger, Harald, et al.
Publicado: (2013)

No association between variation in the NR4A1 gene locus and metabolic traits in white subjects at increased risk for type 2 diabetes
por: Müssig, Karsten, et al.
Publicado: (2010)

Common Genetic Variation in the Human CTF1 Locus, Encoding Cardiotrophin-1, Determines Insulin Sensitivity
por: Lutz, Stefan Z., et al.
Publicado: (2014)

Relationship of Serum Trimethylamine N-Oxide (TMAO) Levels with early Atherosclerosis in Humans
por: Randrianarisoa, Elko, et al.
Publicado: (2016)

Dietary Niacin Intake Predicts the Decrease of Liver Fat Content During a Lifestyle Intervention
por: Linder, Katarzyna, et al.
Publicado: (2019)

Medium Chain Acylcarnitines Dominate the Metabolite Pattern in Humans under Moderate Intensity Exercise and Support Lipid Oxidation
por: Lehmann, Rainer, et al.
Publicado: (2010)

Muscle-Derived Angiopoietin-Like Protein 4 Is Induced by Fatty Acids via Peroxisome Proliferator–Activated Receptor (PPAR)-δ and Is of Metabolic Relevance in Humans
por: Staiger, Harald, et al.
Publicado: (2009)

Diabetes and Nonalcoholic Fatty Liver Disease
por: Kantartzis, Konstantinos, et al.
Publicado: (2012)

Single Nucleotide Polymorphisms in the G-Protein Coupled Receptor Kinase 5 (GRK5) Gene are associated with Plasma LDL-Cholesterol Levels in Humans
por: Lutz, Stefan Z., et al.
Publicado: (2018)

Common Genetic Variation in the SERPINF1 Locus Determines Overall Adiposity, Obesity-Related Insulin Resistance, and Circulating Leptin Levels
por: Böhm, Anja, et al.
Publicado: (2012)

The D299G/T399I Toll-Like Receptor 4 Variant Associates with Body and Liver Fat: Results from the TULIP and METSIM Studies
por: Weyrich, Peter, et al.
Publicado: (2010)

Gene Variants of TCF7L2 Influence Weight Loss and Body Composition During Lifestyle Intervention in a Population at Risk for Type 2 Diabetes
por: Haupt, Axel, et al.
Publicado: (2010)

Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers
por: Kächele, Martin, et al.
Publicado: (2015)

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes
por: Berti, Lucia, et al.
Publicado: (2015)

SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention – the TULIP Study
por: Weyrich, Peter, et al.
Publicado: (2008)

Metabolic Signatures of Cultured Human Adipocytes from Metabolically Healthy versus Unhealthy Obese Individuals
por: Böhm, Anja, et al.
Publicado: (2014)

Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention
por: Wagner, Robert, et al.
Publicado: (2023)

Free fatty acids, glicentin and glucose-dependent insulinotropic polypeptide as potential major determinants of fasting substrate oxidation
por: Hummel, Julia, et al.
Publicado: (2021)

Increased mitochondrial respiration of adipocytes from metabolically unhealthy obese compared to healthy obese individuals
por: Böhm, Anja, et al.
Publicado: (2020)

The German Gestational Diabetes Study (PREG), a prospective multicentre cohort study: rationale, methodology and design
por: Fritsche, Louise, et al.
Publicado: (2022)

Normalized Indices Derived from Visceral Adipose Mass Assessed by Magnetic Resonance Imaging and Their Correlation with Markers for Insulin Resistance and Prediabetes
por: Machann, Jürgen, et al.
Publicado: (2020)

Pancreatic Steatosis Associates With Impaired Insulin Secretion in Genetically Predisposed Individuals
por: Wagner, Róbert, et al.
Publicado: (2020)

Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits
por: Zhao, Xinjie, et al.
Publicado: (2010)

Detection and Characterization of Phosphorylation, Glycosylation, and Fatty Acid Bound to Fetuin A in Human Blood
por: Kovářová, Markéta, et al.
Publicado: (2021)

Detection of diabetes from whole-body MRI using deep learning
por: Dietz, Benedikt, et al.
Publicado: (2021)

Novel Meta-Analysis-Derived Type 2 Diabetes Risk Loci Do Not Determine Prediabetic Phenotypes
por: Staiger, Harald, et al.
Publicado: (2008)

Polymorphisms within the Novel Type 2 Diabetes Risk Locus MTNR1B Determine β-Cell Function
por: Staiger, Harald, et al.
Publicado: (2008)

Polymorphisms within Novel Risk Loci for Type 2 Diabetes Determine β-Cell Function
por: Staiger, Harald, et al.
Publicado: (2007)

Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin
por: Keuper, Michaela, et al.
Publicado: (2018)

Evaluation of Fasting State-/Oral Glucose Tolerance Test-Derived Measures of Insulin Release for the Detection of Genetically Impaired β-Cell Function
por: Herzberg-Schäfer, Silke A., et al.
Publicado: (2010)

Ectopic fat accumulation in human astrocytes impairs insulin action
por: Heni, Martin, et al.
Publicado: (2020)

Extracellular Matrix Expression in Human Pancreatic Fat Cells of Patients with Normal Glucose Regulation, Prediabetes and Type 2 Diabetes
por: Siegel-Axel, Dorothea, et al.
Publicado: (2023)

Glucose tolerance and insulin sensitivity define adipocyte transcriptional programs in human obesity
por: Gerlini, R., et al.
Publicado: (2018)

The protective effect of human renal sinus fat on glomerular cells is reversed by the hepatokine fetuin-A
por: Wagner, R., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_990d32dbksbltotsuu1nutnhmf