Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart

The recently described exchange protein directly activated by cAMP (Epac) has been implicated in distinct protein kinase A-independent cellular signalling pathways. We investigated the role of Epac activation in adrenergically mediated ventricular arrhythmogenesis. In contrast to observations in con...

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Detalles Bibliográficos
Autores principales: Hothi, Sandeep S., Gurung, Iman S., Heathcote, Jennifer C., Zhang, Yanmin, Booth, Stephen W., Skepper, Jeremy N., Grace, Andrew A., Huang, Christopher L.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Cardiovascular Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714550/
https://www.ncbi.nlm.nih.gov/pubmed/18600344
http://dx.doi.org/10.1007/s00424-008-0508-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714550/
https://www.ncbi.nlm.nih.gov/pubmed/18600344
http://dx.doi.org/10.1007/s00424-008-0508-3

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