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Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart

The recently described exchange protein directly activated by cAMP (Epac) has been implicated in distinct protein kinase A-independent cellular signalling pathways. We investigated the role of Epac activation in adrenergically mediated ventricular arrhythmogenesis. In contrast to observations in con...

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Detalles Bibliográficos
Autores principales:	Hothi, Sandeep S., Gurung, Iman S., Heathcote, Jennifer C., Zhang, Yanmin, Booth, Stephen W., Skepper, Jeremy N., Grace, Andrew A., Huang, Christopher L.-H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2008
Materias:	Cardiovascular Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714550/ https://www.ncbi.nlm.nih.gov/pubmed/18600344 http://dx.doi.org/10.1007/s00424-008-0508-3

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