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Relation between platelet indices and branch retinal vein occlusion in hypertensive patients

BACKGROUD: Branch retinal vein occlusion (BRVO) is the second most common retinal vascular disease after diabetic retinopathy. To date, the studies were unable to elucidate the mechanism of the thrombosis leading to the entity; particularly the relation between thrombocyte aggregation and retinal ve...

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Autores principales: Onder, Halil Ibrahim, Kilic, Ali Cagri, Kaya, Murat, Bulur, Serkan, Onder, Elif, Tunc, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714952/
https://www.ncbi.nlm.nih.gov/pubmed/23619481
http://dx.doi.org/10.4103/0301-4738.111063
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author Onder, Halil Ibrahim
Kilic, Ali Cagri
Kaya, Murat
Bulur, Serkan
Onder, Elif
Tunc, Murat
author_facet Onder, Halil Ibrahim
Kilic, Ali Cagri
Kaya, Murat
Bulur, Serkan
Onder, Elif
Tunc, Murat
author_sort Onder, Halil Ibrahim
collection PubMed
description BACKGROUD: Branch retinal vein occlusion (BRVO) is the second most common retinal vascular disease after diabetic retinopathy. To date, the studies were unable to elucidate the mechanism of the thrombosis leading to the entity; particularly the relation between thrombocyte aggregation and retinal vein occlusion is still unclear. Mean platelet volume (MPV) is a determinant of rate of platelet production and activation, both of which are indices of function of platelets. The relation between MPV and BRVO has not been studied before. The aim was to evaluate MPV in BRVO. MATERIALS AND METHODS: Forty patients were included in the study. Forty six age and sex matched hypertensive volunteers were recruited as the control group. RESULTS: MPV values were significantly higher in BRVO patients compared with the control subjects (8.01 ± 0.79vs 7.52 ± 0.32fL, respectively; P < 0.001). Conclusion: MPV is significantly higher in patients hypertensive BRVO patients and further investigations regarding its potentially use as a prognostic biomarker in patients with BRVO are needed.
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spelling pubmed-37149522013-07-22 Relation between platelet indices and branch retinal vein occlusion in hypertensive patients Onder, Halil Ibrahim Kilic, Ali Cagri Kaya, Murat Bulur, Serkan Onder, Elif Tunc, Murat Indian J Ophthalmol Original Article BACKGROUD: Branch retinal vein occlusion (BRVO) is the second most common retinal vascular disease after diabetic retinopathy. To date, the studies were unable to elucidate the mechanism of the thrombosis leading to the entity; particularly the relation between thrombocyte aggregation and retinal vein occlusion is still unclear. Mean platelet volume (MPV) is a determinant of rate of platelet production and activation, both of which are indices of function of platelets. The relation between MPV and BRVO has not been studied before. The aim was to evaluate MPV in BRVO. MATERIALS AND METHODS: Forty patients were included in the study. Forty six age and sex matched hypertensive volunteers were recruited as the control group. RESULTS: MPV values were significantly higher in BRVO patients compared with the control subjects (8.01 ± 0.79vs 7.52 ± 0.32fL, respectively; P < 0.001). Conclusion: MPV is significantly higher in patients hypertensive BRVO patients and further investigations regarding its potentially use as a prognostic biomarker in patients with BRVO are needed. Medknow Publications & Media Pvt Ltd 2013-04 /pmc/articles/PMC3714952/ /pubmed/23619481 http://dx.doi.org/10.4103/0301-4738.111063 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Onder, Halil Ibrahim
Kilic, Ali Cagri
Kaya, Murat
Bulur, Serkan
Onder, Elif
Tunc, Murat
Relation between platelet indices and branch retinal vein occlusion in hypertensive patients
title Relation between platelet indices and branch retinal vein occlusion in hypertensive patients
title_full Relation between platelet indices and branch retinal vein occlusion in hypertensive patients
title_fullStr Relation between platelet indices and branch retinal vein occlusion in hypertensive patients
title_full_unstemmed Relation between platelet indices and branch retinal vein occlusion in hypertensive patients
title_short Relation between platelet indices and branch retinal vein occlusion in hypertensive patients
title_sort relation between platelet indices and branch retinal vein occlusion in hypertensive patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714952/
https://www.ncbi.nlm.nih.gov/pubmed/23619481
http://dx.doi.org/10.4103/0301-4738.111063
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