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Relation between platelet indices and branch retinal vein occlusion in hypertensive patients
BACKGROUD: Branch retinal vein occlusion (BRVO) is the second most common retinal vascular disease after diabetic retinopathy. To date, the studies were unable to elucidate the mechanism of the thrombosis leading to the entity; particularly the relation between thrombocyte aggregation and retinal ve...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714952/ https://www.ncbi.nlm.nih.gov/pubmed/23619481 http://dx.doi.org/10.4103/0301-4738.111063 |
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author | Onder, Halil Ibrahim Kilic, Ali Cagri Kaya, Murat Bulur, Serkan Onder, Elif Tunc, Murat |
author_facet | Onder, Halil Ibrahim Kilic, Ali Cagri Kaya, Murat Bulur, Serkan Onder, Elif Tunc, Murat |
author_sort | Onder, Halil Ibrahim |
collection | PubMed |
description | BACKGROUD: Branch retinal vein occlusion (BRVO) is the second most common retinal vascular disease after diabetic retinopathy. To date, the studies were unable to elucidate the mechanism of the thrombosis leading to the entity; particularly the relation between thrombocyte aggregation and retinal vein occlusion is still unclear. Mean platelet volume (MPV) is a determinant of rate of platelet production and activation, both of which are indices of function of platelets. The relation between MPV and BRVO has not been studied before. The aim was to evaluate MPV in BRVO. MATERIALS AND METHODS: Forty patients were included in the study. Forty six age and sex matched hypertensive volunteers were recruited as the control group. RESULTS: MPV values were significantly higher in BRVO patients compared with the control subjects (8.01 ± 0.79vs 7.52 ± 0.32fL, respectively; P < 0.001). Conclusion: MPV is significantly higher in patients hypertensive BRVO patients and further investigations regarding its potentially use as a prognostic biomarker in patients with BRVO are needed. |
format | Online Article Text |
id | pubmed-3714952 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37149522013-07-22 Relation between platelet indices and branch retinal vein occlusion in hypertensive patients Onder, Halil Ibrahim Kilic, Ali Cagri Kaya, Murat Bulur, Serkan Onder, Elif Tunc, Murat Indian J Ophthalmol Original Article BACKGROUD: Branch retinal vein occlusion (BRVO) is the second most common retinal vascular disease after diabetic retinopathy. To date, the studies were unable to elucidate the mechanism of the thrombosis leading to the entity; particularly the relation between thrombocyte aggregation and retinal vein occlusion is still unclear. Mean platelet volume (MPV) is a determinant of rate of platelet production and activation, both of which are indices of function of platelets. The relation between MPV and BRVO has not been studied before. The aim was to evaluate MPV in BRVO. MATERIALS AND METHODS: Forty patients were included in the study. Forty six age and sex matched hypertensive volunteers were recruited as the control group. RESULTS: MPV values were significantly higher in BRVO patients compared with the control subjects (8.01 ± 0.79vs 7.52 ± 0.32fL, respectively; P < 0.001). Conclusion: MPV is significantly higher in patients hypertensive BRVO patients and further investigations regarding its potentially use as a prognostic biomarker in patients with BRVO are needed. Medknow Publications & Media Pvt Ltd 2013-04 /pmc/articles/PMC3714952/ /pubmed/23619481 http://dx.doi.org/10.4103/0301-4738.111063 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Onder, Halil Ibrahim Kilic, Ali Cagri Kaya, Murat Bulur, Serkan Onder, Elif Tunc, Murat Relation between platelet indices and branch retinal vein occlusion in hypertensive patients |
title | Relation between platelet indices and branch retinal vein occlusion in hypertensive patients |
title_full | Relation between platelet indices and branch retinal vein occlusion in hypertensive patients |
title_fullStr | Relation between platelet indices and branch retinal vein occlusion in hypertensive patients |
title_full_unstemmed | Relation between platelet indices and branch retinal vein occlusion in hypertensive patients |
title_short | Relation between platelet indices and branch retinal vein occlusion in hypertensive patients |
title_sort | relation between platelet indices and branch retinal vein occlusion in hypertensive patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714952/ https://www.ncbi.nlm.nih.gov/pubmed/23619481 http://dx.doi.org/10.4103/0301-4738.111063 |
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