FTY720 induces apoptosis in B16F10-NEX2 murine melanoma cells, limits metastatic development in vivo, and modulates the immune system

OBJECTIVE: Available chemotherapy presents poor control over the development of metastatic melanoma. FTY720 is a compound already approved by the Food and Drug Administration for the treatment of patients with multiple sclerosis. It has also been observed that FTY720 inhibits tumor growth in vivo (e...

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Detalles Bibliográficos
Autores principales: Pereira, Felipe V., Arruda, Denise C., Figueiredo, Carlos R., Massaoka, Mariana H., Matsuo, Alisson L., Bueno, Valquiria, Rodrigues, Elaine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2013
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715017/
https://www.ncbi.nlm.nih.gov/pubmed/23917669
http://dx.doi.org/10.6061/clinics/2013(07)21

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