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Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals

Type 1 diabetes (T1D) is an autoimmune disease characterized by known genetic risk factors with T cell–mediated infiltration and destruction of the beta cells within pancreatic islets. Autoantibodies are the most significant preclinical marker of T1D, and birth cohort studies have provided important...

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Detalles Bibliográficos
Autores principales: Nokoff, Natalie, Rewers, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715099/
https://www.ncbi.nlm.nih.gov/pubmed/23360422
http://dx.doi.org/10.1111/nyas.12021