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Mycobacterium tuberculosis Nucleoside Diphosphate Kinase Inactivates Small GTPases Leading to Evasion of Innate Immunity

Defining the mechanisms of Mycobacterium tuberculosis (Mtb) persistence in the host macrophage and identifying mycobacterial factors responsible for it are keys to better understand tuberculosis pathogenesis. The emerging picture from ongoing studies of macrophage deactivation by Mtb suggests that i...

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Detalles Bibliográficos
Autores principales: Sun, Jim, Singh, Vijender, Lau, Alice, Stokes, Richard W., Obregón-Henao, Andrés, Orme, Ian M., Wong, Dennis, Av-Gay, Yossef, Hmama, Zakaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715411/
https://www.ncbi.nlm.nih.gov/pubmed/23874203
http://dx.doi.org/10.1371/journal.ppat.1003499