HIF-1α Is Essential for Effective PMN Bacterial Killing, Antimicrobial Peptide Production and Apoptosis in Pseudomonas aeruginosa Keratitis

Hypoxia-inducible factor (HIF)-1α, is a transcription factor that controls energy metabolism and angiogenesis under hypoxic conditions, and a potent regulator of innate immunity. The studies described herein examined the role of HIF-1α in disease resolution in BALB/c (resistant, cornea heals) mice a...

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Detalles Bibliográficos
Autores principales: Berger, Elizabeth A., McClellan, Sharon A., Vistisen, Kerry S., Hazlett, Linda D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715414/
https://www.ncbi.nlm.nih.gov/pubmed/23874197
http://dx.doi.org/10.1371/journal.ppat.1003457

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