Genome-Wide Association Mapping in Dogs Enables Identification of the Homeobox Gene, NKX2-8, as a Genetic Component of Neural Tube Defects in Humans

Neural tube defects (NTDs) is a general term for central nervous system malformations secondary to a failure of closure or development of the neural tube. The resulting pathologies may involve the brain, spinal cord and/or vertebral column, in addition to associated structures such as soft tissue or...

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Detalles Bibliográficos
Autores principales: Safra, Noa, Bassuk, Alexander G., Ferguson, Polly J., Aguilar, Miriam, Coulson, Rochelle L., Thomas, Nicholas, Hitchens, Peta L., Dickinson, Peter J., Vernau, Karen M., Wolf, Zena T., Bannasch, Danika L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715436/
https://www.ncbi.nlm.nih.gov/pubmed/23874236
http://dx.doi.org/10.1371/journal.pgen.1003646

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