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Significant Impact of the MTHFR Polymorphisms and Haplotypes on Male Infertility Risk

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) converts 5,10-methylene tetrahydrofolate to 5-methyl tetrahydrofolate and affects the activity of cellular cycles participating in nucleotide synthesis, DNA repair, genome stability, maintenance of methyl pool, and gene regulation. Genetically...

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Detalles Bibliográficos
Autores principales: Gupta, Nishi, Sarkar, Saumya, David, Archana, Gangwar, Pravin Kumar, Gupta, Richa, Khanna, Gita, Sankhwar, Satya Narayan, Khanna, Anil, Rajender, Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715460/
https://www.ncbi.nlm.nih.gov/pubmed/23874907
http://dx.doi.org/10.1371/journal.pone.0069180

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