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Normalizing RNA-Sequencing Data by Modeling Hidden Covariates with Prior Knowledge
Transcriptomic assays that measure expression levels are widely used to study the manifestation of environmental or genetic variations in cellular processes. RNA-sequencing in particular has the potential to considerably improve such understanding because of its capacity to assay the entire transcri...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715474/ https://www.ncbi.nlm.nih.gov/pubmed/23874524 http://dx.doi.org/10.1371/journal.pone.0068141 |