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QuateXelero: An Accelerated Exact Network Motif Detection Algorithm

Finding motifs in biological, social, technological, and other types of networks has become a widespread method to gain more knowledge about these networks’ structure and function. However, this task is very computationally demanding, because it is highly associated with the graph isomorphism which...

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Detalles Bibliográficos
Autores principales: Khakabimamaghani, Sahand, Sharafuddin, Iman, Dichter, Norbert, Koch, Ina, Masoudi-Nejad, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715482/
https://www.ncbi.nlm.nih.gov/pubmed/23874498
http://dx.doi.org/10.1371/journal.pone.0068073
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author Khakabimamaghani, Sahand
Sharafuddin, Iman
Dichter, Norbert
Koch, Ina
Masoudi-Nejad, Ali
author_facet Khakabimamaghani, Sahand
Sharafuddin, Iman
Dichter, Norbert
Koch, Ina
Masoudi-Nejad, Ali
author_sort Khakabimamaghani, Sahand
collection PubMed
description Finding motifs in biological, social, technological, and other types of networks has become a widespread method to gain more knowledge about these networks’ structure and function. However, this task is very computationally demanding, because it is highly associated with the graph isomorphism which is an NP problem (not known to belong to P or NP-complete subsets yet). Accordingly, this research is endeavoring to decrease the need to call NAUTY isomorphism detection method, which is the most time-consuming step in many existing algorithms. The work provides an extremely fast motif detection algorithm called QuateXelero, which has a Quaternary Tree data structure in the heart. The proposed algorithm is based on the well-known ESU (FANMOD) motif detection algorithm. The results of experiments on some standard model networks approve the overal superiority of the proposed algorithm, namely QuateXelero, compared with two of the fastest existing algorithms, G-Tries and Kavosh. QuateXelero is especially fastest in constructing the central data structure of the algorithm from scratch based on the input network.
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spelling pubmed-37154822013-07-19 QuateXelero: An Accelerated Exact Network Motif Detection Algorithm Khakabimamaghani, Sahand Sharafuddin, Iman Dichter, Norbert Koch, Ina Masoudi-Nejad, Ali PLoS One Research Article Finding motifs in biological, social, technological, and other types of networks has become a widespread method to gain more knowledge about these networks’ structure and function. However, this task is very computationally demanding, because it is highly associated with the graph isomorphism which is an NP problem (not known to belong to P or NP-complete subsets yet). Accordingly, this research is endeavoring to decrease the need to call NAUTY isomorphism detection method, which is the most time-consuming step in many existing algorithms. The work provides an extremely fast motif detection algorithm called QuateXelero, which has a Quaternary Tree data structure in the heart. The proposed algorithm is based on the well-known ESU (FANMOD) motif detection algorithm. The results of experiments on some standard model networks approve the overal superiority of the proposed algorithm, namely QuateXelero, compared with two of the fastest existing algorithms, G-Tries and Kavosh. QuateXelero is especially fastest in constructing the central data structure of the algorithm from scratch based on the input network. Public Library of Science 2013-07-18 /pmc/articles/PMC3715482/ /pubmed/23874498 http://dx.doi.org/10.1371/journal.pone.0068073 Text en © 2013 Khakabimamaghani et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Khakabimamaghani, Sahand
Sharafuddin, Iman
Dichter, Norbert
Koch, Ina
Masoudi-Nejad, Ali
QuateXelero: An Accelerated Exact Network Motif Detection Algorithm
title QuateXelero: An Accelerated Exact Network Motif Detection Algorithm
title_full QuateXelero: An Accelerated Exact Network Motif Detection Algorithm
title_fullStr QuateXelero: An Accelerated Exact Network Motif Detection Algorithm
title_full_unstemmed QuateXelero: An Accelerated Exact Network Motif Detection Algorithm
title_short QuateXelero: An Accelerated Exact Network Motif Detection Algorithm
title_sort quatexelero: an accelerated exact network motif detection algorithm
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715482/
https://www.ncbi.nlm.nih.gov/pubmed/23874498
http://dx.doi.org/10.1371/journal.pone.0068073
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