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Low Molecular Weight Heparin Relieves Experimental Colitis in Mice by Downregulating IL-1β and Inhibiting Syndecan-1 Shedding in the Intestinal Mucosa
Low molecular weight heparin (LMWH) exhibits anti-inflammatory properties, but its effect on inflammation in colitis remains unclear. This study aimed to evaluate the therapeutic effects of LMWH on dextran sulfate sodium (DSS)-induced colitis in mice, in which acute colitis progresses to chronic col...
Autores principales: | Wang, Xian-fei, Li, Ai-ming, Li, Jing, Lin, Shi-yong, Chen, Chu-di, Zhou, You-lian, Wang, Xia, Chen, Cun-long, Liu, Si-de, Chen, Ye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715511/ https://www.ncbi.nlm.nih.gov/pubmed/23874391 http://dx.doi.org/10.1371/journal.pone.0066397 |
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