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Dynamic Fluctuations Provide the Basis of a Conformational Switch Mechanism in Apo Cyclic AMP Receptor Protein

Escherichia coli cyclic AMP Receptor Protein (CRP) undergoes conformational changes with cAMP binding and allosterically promotes CRP to bind specifically to the DNA. In that, the structural and dynamic properties of apo CRP prior to cAMP binding are of interest for the comprehension of the activati...

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Detalles Bibliográficos
Autores principales:	Aykaç Fas, Burcu, Tutar, Yusuf, Haliloğlu, Türkan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715548/ https://www.ncbi.nlm.nih.gov/pubmed/23874183 http://dx.doi.org/10.1371/journal.pcbi.1003141

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