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Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA
Two novel macrocyclic polyamine ligands and their dinuclear zinc (II) complexes were synthesized and characterized. Their interaction with plasmid DNA was studied by gel electrophoresis and fluorescence quenching experiment. The result showed that these complexes could bind DNA efficiently under phy...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716430/ |
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author | Huang, Jun Huang, Qing-Dong Zhang, Ji Zhou, Li-Hong Li, Qiang-Lin Li, Kun Jiang, Ning Lin, Hong-Hui Wu, Jiang Yu, Xiao-Qi |
author_facet | Huang, Jun Huang, Qing-Dong Zhang, Ji Zhou, Li-Hong Li, Qiang-Lin Li, Kun Jiang, Ning Lin, Hong-Hui Wu, Jiang Yu, Xiao-Qi |
author_sort | Huang, Jun |
collection | PubMed |
description | Two novel macrocyclic polyamine ligands and their dinuclear zinc (II) complexes were synthesized and characterized. Their interaction with plasmid DNA was studied by gel electrophoresis and fluorescence quenching experiment. The result showed that these complexes could bind DNA efficiently under physiological conditions. |
format | Online Article Text |
id | pubmed-3716430 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-37164302013-07-22 Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA Huang, Jun Huang, Qing-Dong Zhang, Ji Zhou, Li-Hong Li, Qiang-Lin Li, Kun Jiang, Ning Lin, Hong-Hui Wu, Jiang Yu, Xiao-Qi Int J Mol Sci Full Research Paper Two novel macrocyclic polyamine ligands and their dinuclear zinc (II) complexes were synthesized and characterized. Their interaction with plasmid DNA was studied by gel electrophoresis and fluorescence quenching experiment. The result showed that these complexes could bind DNA efficiently under physiological conditions. Molecular Diversity Preservation International (MDPI) 2007-07-04 /pmc/articles/PMC3716430/ Text en © 2007 by MDPI (http://www.mdpi.org) Reproduction is permitted for noncommercial purposes. |
spellingShingle | Full Research Paper Huang, Jun Huang, Qing-Dong Zhang, Ji Zhou, Li-Hong Li, Qiang-Lin Li, Kun Jiang, Ning Lin, Hong-Hui Wu, Jiang Yu, Xiao-Qi Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA |
title | Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA |
title_full | Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA |
title_fullStr | Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA |
title_full_unstemmed | Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA |
title_short | Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA |
title_sort | dinuclear zinc (ii) complexes of macrocyclic polyamine ligands containing an imidazolium bridge: synthesis, characterization, and their interaction with plasmid dna |
topic | Full Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716430/ |
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