Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA

Two novel macrocyclic polyamine ligands and their dinuclear zinc (II) complexes were synthesized and characterized. Their interaction with plasmid DNA was studied by gel electrophoresis and fluorescence quenching experiment. The result showed that these complexes could bind DNA efficiently under phy...

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Autores principales: Huang, Jun, Huang, Qing-Dong, Zhang, Ji, Zhou, Li-Hong, Li, Qiang-Lin, Li, Kun, Jiang, Ning, Lin, Hong-Hui, Wu, Jiang, Yu, Xiao-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2007
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716430/
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author Huang, Jun
Huang, Qing-Dong
Zhang, Ji
Zhou, Li-Hong
Li, Qiang-Lin
Li, Kun
Jiang, Ning
Lin, Hong-Hui
Wu, Jiang
Yu, Xiao-Qi
author_facet Huang, Jun
Huang, Qing-Dong
Zhang, Ji
Zhou, Li-Hong
Li, Qiang-Lin
Li, Kun
Jiang, Ning
Lin, Hong-Hui
Wu, Jiang
Yu, Xiao-Qi
author_sort Huang, Jun
collection PubMed
description Two novel macrocyclic polyamine ligands and their dinuclear zinc (II) complexes were synthesized and characterized. Their interaction with plasmid DNA was studied by gel electrophoresis and fluorescence quenching experiment. The result showed that these complexes could bind DNA efficiently under physiological conditions.
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spelling pubmed-37164302013-07-22 Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA Huang, Jun Huang, Qing-Dong Zhang, Ji Zhou, Li-Hong Li, Qiang-Lin Li, Kun Jiang, Ning Lin, Hong-Hui Wu, Jiang Yu, Xiao-Qi Int J Mol Sci Full Research Paper Two novel macrocyclic polyamine ligands and their dinuclear zinc (II) complexes were synthesized and characterized. Their interaction with plasmid DNA was studied by gel electrophoresis and fluorescence quenching experiment. The result showed that these complexes could bind DNA efficiently under physiological conditions. Molecular Diversity Preservation International (MDPI) 2007-07-04 /pmc/articles/PMC3716430/ Text en © 2007 by MDPI (http://www.mdpi.org) Reproduction is permitted for noncommercial purposes.
spellingShingle Full Research Paper
Huang, Jun
Huang, Qing-Dong
Zhang, Ji
Zhou, Li-Hong
Li, Qiang-Lin
Li, Kun
Jiang, Ning
Lin, Hong-Hui
Wu, Jiang
Yu, Xiao-Qi
Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA
title Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA
title_full Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA
title_fullStr Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA
title_full_unstemmed Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA
title_short Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA
title_sort dinuclear zinc (ii) complexes of macrocyclic polyamine ligands containing an imidazolium bridge: synthesis, characterization, and their interaction with plasmid dna
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716430/
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