Modification of Low Molecular Weight Polysaccharides from Tremella Fuciformis and Their Antioxidant Activity in Vitro

In this study, sulfated low molecular-weight Tremella fuciformis polysaccharides (SLTP) with different sulfate contents were synthesized and their antioxidant activities, including superoxide anion radical, 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical and hydroxyl radical scavenging activities were...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Zheng, Cheng, Ning, Zheng-Xiang, Yang, Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2007
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Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716436/
Descripción
Sumario:In this study, sulfated low molecular-weight Tremella fuciformis polysaccharides (SLTP) with different sulfate contents were synthesized and their antioxidant activities, including superoxide anion radical, 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical and hydroxyl radical scavenging activities were investigated. The results indicated that, compared to natural Tremella fuciformis polysaccharide (TP) and low molecular weight Tremella fuciformis polysaccharide (LTP), sulfated LTP (SLTP) exhibited stronger scavenging activity towards superoxide anion, DPPH and hydroxyl radicals. In all the cases the effect was found to be dose dependent. The scavenging activity of SLTP was found to be in parallel with the degree of sulfation of SLTP.

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