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Static Mechanical Stress Induces Apoptosis in Rat Endplate Chondrocytes through MAPK and Mitochondria-Dependent Caspase Activation Signaling Pathways

Mechanical stress has detrimental effects on cartilaginous endplate chondrocytes due to apoptosis in vivo and in vitro. In this study, we investigated the possible apoptosis signaling pathways induced by mechanical stress in cultured rat cervical endplate chondrocytes. Static mechanical load signifi...

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Detalles Bibliográficos
Autores principales: Kong, Dechao, Zheng, Tiansheng, Zhang, Ming, Wang, Daode, Du, Shihao, Li, Xiang, Fang, Jiahu, Cao, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716647/
https://www.ncbi.nlm.nih.gov/pubmed/23894471
http://dx.doi.org/10.1371/journal.pone.0069403