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The N-end rule and retroviral infection: no effect on integrase

BACKGROUND: Integration of double stranded viral DNA is a key step in the retroviral life cycle. Virally encoded enzyme, integrase, plays a central role in this reaction. Mature forms of integrase of several retroviruses (i.e. HIV-1 and MLV) bear conserved destabilizing N-terminal residues of the N-...

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Detalles Bibliográficos
Autores principales:	Boso, Guney, Tasaki, Takafumi, Kwon, Yong Tae, Somia, Nikunj V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716682/ https://www.ncbi.nlm.nih.gov/pubmed/23849394 http://dx.doi.org/10.1186/1743-422X-10-233

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