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Functional Loss of Two Ceramide Synthases Elicits Autophagy-Dependent Lifespan Extension in C. elegans

Ceramide and its metabolites constitute a diverse group of lipids, which play important roles as structural entities of biological membranes as well as regulators of cellular growth, differentiation, and development. The C. elegans genome comprises three ceramide synthase genes; hyl-1, hyl-2, and la...

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Detalles Bibliográficos
Autores principales:	Mosbech, Mai-Britt, Kruse, Rikke, Harvald, Eva Bang, Olsen, Anne Sofie Braun, Gallego, Sandra Fernandez, Hannibal-Bach, Hans Kristian, Ejsing, Christer S., Færgeman, Nils J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716707/ https://www.ncbi.nlm.nih.gov/pubmed/23894595 http://dx.doi.org/10.1371/journal.pone.0070087

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