Cargando…

A self antigen reopens the games in pancreatic cancer

We have recently demonstrated that the administration of a plasmid coding for α-enolase can elicit robust immune responses in genetically engineered mice that spontaneously develop pancreatic cancer, resulting in a significant improvement of their survival. This approach provides a springboard for t...

Descripción completa

Detalles Bibliográficos
Autores principales: Cappello, Paola, Novelli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716733/
https://www.ncbi.nlm.nih.gov/pubmed/23894698
http://dx.doi.org/10.4161/onci.24384
_version_ 1782277587178881024
author Cappello, Paola
Novelli, Francesco
author_facet Cappello, Paola
Novelli, Francesco
author_sort Cappello, Paola
collection PubMed
description We have recently demonstrated that the administration of a plasmid coding for α-enolase can elicit robust immune responses in genetically engineered mice that spontaneously develop pancreatic cancer, resulting in a significant improvement of their survival. This approach provides a springboard for the elaboration of new forms of immunotherapy for pancreatic cancer.
format Online
Article
Text
id pubmed-3716733
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Landes Bioscience
record_format MEDLINE/PubMed
spelling pubmed-37167332013-07-26 A self antigen reopens the games in pancreatic cancer Cappello, Paola Novelli, Francesco Oncoimmunology Author's View We have recently demonstrated that the administration of a plasmid coding for α-enolase can elicit robust immune responses in genetically engineered mice that spontaneously develop pancreatic cancer, resulting in a significant improvement of their survival. This approach provides a springboard for the elaboration of new forms of immunotherapy for pancreatic cancer. Landes Bioscience 2013-06-01 2013-05-10 /pmc/articles/PMC3716733/ /pubmed/23894698 http://dx.doi.org/10.4161/onci.24384 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Cappello, Paola
Novelli, Francesco
A self antigen reopens the games in pancreatic cancer
title A self antigen reopens the games in pancreatic cancer
title_full A self antigen reopens the games in pancreatic cancer
title_fullStr A self antigen reopens the games in pancreatic cancer
title_full_unstemmed A self antigen reopens the games in pancreatic cancer
title_short A self antigen reopens the games in pancreatic cancer
title_sort self antigen reopens the games in pancreatic cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716733/
https://www.ncbi.nlm.nih.gov/pubmed/23894698
http://dx.doi.org/10.4161/onci.24384
work_keys_str_mv AT cappellopaola aselfantigenreopensthegamesinpancreaticcancer
AT novellifrancesco aselfantigenreopensthegamesinpancreaticcancer
AT cappellopaola selfantigenreopensthegamesinpancreaticcancer
AT novellifrancesco selfantigenreopensthegamesinpancreaticcancer