Catechins and antitumor immunity: Not MDSC’s cup of tea

Numerous laboratory and clinical studies have reported that the green tea catechin extract Polyphenon E exert anticancer activity, but the underlying mechanism of action was elusive. We have recently shown that Polyphenon E exerts antineoplastic effects by antagonizing tumor-induced myeloid derived...

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Detalles Bibliográficos
Autores principales: Santilli, Giorgia, Anderson, John, Thrasher, Adrian J, Sala, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716739/
https://www.ncbi.nlm.nih.gov/pubmed/23894704
http://dx.doi.org/10.4161/onci.24443
Descripción
Sumario:Numerous laboratory and clinical studies have reported that the green tea catechin extract Polyphenon E exert anticancer activity, but the underlying mechanism of action was elusive. We have recently shown that Polyphenon E exerts antineoplastic effects by antagonizing tumor-induced myeloid derived suppressor cells (MDSCs).

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