IL-21 in cancer immunotherapy: At the right place at the right time

Interleukin-21 (IL-21) has been described as a potent stimulator of antitumor T-cell immunity, but also of autoimmune reactions and oncogenesis. Antigen presenting cells genetically modified to release IL-21 allow for the expansion of tumor-specific T cells exhibiting favorable effector and growth c...

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Detalles Bibliográficos
Autores principales: Santegoets, Saskia JAM, Turksma, Annelies W., Powell Jr., Daniel J, Hooijberg, Erik, de Gruijl, Tanja D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716748/
https://www.ncbi.nlm.nih.gov/pubmed/23894713
http://dx.doi.org/10.4161/onci.24522

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