A co-stimulatory trap set by myeloid leukemia cells

The straightforward notion that tumor cells always exert immunosuppressive functions has been contradicted by the finding that myeloid leukemia cells can express potent co-stimulatory molecules. Indeed, the co-stimulatory support offered by leukemia cells can provoke helper T-cell responses. Unfavor...

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Detalles Bibliográficos
Autor principal: Esendagli, Gunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716749/
https://www.ncbi.nlm.nih.gov/pubmed/23894714
http://dx.doi.org/10.4161/onci.24524
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author Esendagli, Gunes
author_facet Esendagli, Gunes
author_sort Esendagli, Gunes
collection PubMed
description The straightforward notion that tumor cells always exert immunosuppressive functions has been contradicted by the finding that myeloid leukemia cells can express potent co-stimulatory molecules. Indeed, the co-stimulatory support offered by leukemia cells can provoke helper T-cell responses. Unfavorably, this interaction allows leukemia cells to acquire immunosuppressive capacities.
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spelling pubmed-37167492013-07-26 A co-stimulatory trap set by myeloid leukemia cells Esendagli, Gunes Oncoimmunology Author's View The straightforward notion that tumor cells always exert immunosuppressive functions has been contradicted by the finding that myeloid leukemia cells can express potent co-stimulatory molecules. Indeed, the co-stimulatory support offered by leukemia cells can provoke helper T-cell responses. Unfavorably, this interaction allows leukemia cells to acquire immunosuppressive capacities. Landes Bioscience 2013-06-01 2013-05-23 /pmc/articles/PMC3716749/ /pubmed/23894714 http://dx.doi.org/10.4161/onci.24524 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Esendagli, Gunes
A co-stimulatory trap set by myeloid leukemia cells
title A co-stimulatory trap set by myeloid leukemia cells
title_full A co-stimulatory trap set by myeloid leukemia cells
title_fullStr A co-stimulatory trap set by myeloid leukemia cells
title_full_unstemmed A co-stimulatory trap set by myeloid leukemia cells
title_short A co-stimulatory trap set by myeloid leukemia cells
title_sort co-stimulatory trap set by myeloid leukemia cells
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716749/
https://www.ncbi.nlm.nih.gov/pubmed/23894714
http://dx.doi.org/10.4161/onci.24524
work_keys_str_mv AT esendagligunes acostimulatorytrapsetbymyeloidleukemiacells
AT esendagligunes costimulatorytrapsetbymyeloidleukemiacells

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