ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy

Tumor cells succumb to chemotherapy while releasing ATP. We have found that extracellular ATP attracts dendritic cell (DC) precursors into the tumor bed, facilitates their permanence in the proximity of dying cells and promotes their differentiation into mature DCs endowed with the capacity of prese...

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Autores principales: Ma, Yuting, Adjemian, Sandy, Yang, Heng, Catani, João Paulo Portela, Hannani, Dalil, Martins, Isabelle, Michaud, Mickaël, Kepp, Oliver, Sukkurwala, Abdul Qader, Vacchelli, Erika, Galluzzi, Lorenzo, Zitvogel, Laurence, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716753/
https://www.ncbi.nlm.nih.gov/pubmed/23894718
http://dx.doi.org/10.4161/onci.24568
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author Ma, Yuting
Adjemian, Sandy
Yang, Heng
Catani, João Paulo Portela
Hannani, Dalil
Martins, Isabelle
Michaud, Mickaël
Kepp, Oliver
Sukkurwala, Abdul Qader
Vacchelli, Erika
Galluzzi, Lorenzo
Zitvogel, Laurence
Kroemer, Guido
author_facet Ma, Yuting
Adjemian, Sandy
Yang, Heng
Catani, João Paulo Portela
Hannani, Dalil
Martins, Isabelle
Michaud, Mickaël
Kepp, Oliver
Sukkurwala, Abdul Qader
Vacchelli, Erika
Galluzzi, Lorenzo
Zitvogel, Laurence
Kroemer, Guido
author_sort Ma, Yuting
collection PubMed
description Tumor cells succumb to chemotherapy while releasing ATP. We have found that extracellular ATP attracts dendritic cell (DC) precursors into the tumor bed, facilitates their permanence in the proximity of dying cells and promotes their differentiation into mature DCs endowed with the capacity of presenting tumor-associated antigens.
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spelling pubmed-37167532013-07-26 ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy Ma, Yuting Adjemian, Sandy Yang, Heng Catani, João Paulo Portela Hannani, Dalil Martins, Isabelle Michaud, Mickaël Kepp, Oliver Sukkurwala, Abdul Qader Vacchelli, Erika Galluzzi, Lorenzo Zitvogel, Laurence Kroemer, Guido Oncoimmunology Author's View Tumor cells succumb to chemotherapy while releasing ATP. We have found that extracellular ATP attracts dendritic cell (DC) precursors into the tumor bed, facilitates their permanence in the proximity of dying cells and promotes their differentiation into mature DCs endowed with the capacity of presenting tumor-associated antigens. Landes Bioscience 2013-06-01 2013-04-16 /pmc/articles/PMC3716753/ /pubmed/23894718 http://dx.doi.org/10.4161/onci.24568 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Ma, Yuting
Adjemian, Sandy
Yang, Heng
Catani, João Paulo Portela
Hannani, Dalil
Martins, Isabelle
Michaud, Mickaël
Kepp, Oliver
Sukkurwala, Abdul Qader
Vacchelli, Erika
Galluzzi, Lorenzo
Zitvogel, Laurence
Kroemer, Guido
ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy
title ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy
title_full ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy
title_fullStr ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy
title_full_unstemmed ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy
title_short ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy
title_sort atp-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716753/
https://www.ncbi.nlm.nih.gov/pubmed/23894718
http://dx.doi.org/10.4161/onci.24568
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