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Interferons in hematopoiesis and leukemia
Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Unders...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716754/ https://www.ncbi.nlm.nih.gov/pubmed/23894719 http://dx.doi.org/10.4161/onci.24572 |
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author | Schürch, Christian M Riether, Carsten Ochsenbein, Adrian F |
author_facet | Schürch, Christian M Riether, Carsten Ochsenbein, Adrian F |
author_sort | Schürch, Christian M |
collection | PubMed |
description | Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Understanding these mechanisms may lead to novel therapeutic approaches against leukemia. |
format | Online Article Text |
id | pubmed-3716754 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-37167542013-07-26 Interferons in hematopoiesis and leukemia Schürch, Christian M Riether, Carsten Ochsenbein, Adrian F Oncoimmunology Author's View Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Understanding these mechanisms may lead to novel therapeutic approaches against leukemia. Landes Bioscience 2013-06-01 2013-04-16 /pmc/articles/PMC3716754/ /pubmed/23894719 http://dx.doi.org/10.4161/onci.24572 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Author's View Schürch, Christian M Riether, Carsten Ochsenbein, Adrian F Interferons in hematopoiesis and leukemia |
title | Interferons in hematopoiesis and leukemia |
title_full | Interferons in hematopoiesis and leukemia |
title_fullStr | Interferons in hematopoiesis and leukemia |
title_full_unstemmed | Interferons in hematopoiesis and leukemia |
title_short | Interferons in hematopoiesis and leukemia |
title_sort | interferons in hematopoiesis and leukemia |
topic | Author's View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716754/ https://www.ncbi.nlm.nih.gov/pubmed/23894719 http://dx.doi.org/10.4161/onci.24572 |
work_keys_str_mv | AT schurchchristianm interferonsinhematopoiesisandleukemia AT riethercarsten interferonsinhematopoiesisandleukemia AT ochsenbeinadrianf interferonsinhematopoiesisandleukemia |