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Interferons in hematopoiesis and leukemia

Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Unders...

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Detalles Bibliográficos
Autores principales: Schürch, Christian M, Riether, Carsten, Ochsenbein, Adrian F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716754/
https://www.ncbi.nlm.nih.gov/pubmed/23894719
http://dx.doi.org/10.4161/onci.24572
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author Schürch, Christian M
Riether, Carsten
Ochsenbein, Adrian F
author_facet Schürch, Christian M
Riether, Carsten
Ochsenbein, Adrian F
author_sort Schürch, Christian M
collection PubMed
description Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Understanding these mechanisms may lead to novel therapeutic approaches against leukemia.
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spelling pubmed-37167542013-07-26 Interferons in hematopoiesis and leukemia Schürch, Christian M Riether, Carsten Ochsenbein, Adrian F Oncoimmunology Author's View Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Understanding these mechanisms may lead to novel therapeutic approaches against leukemia. Landes Bioscience 2013-06-01 2013-04-16 /pmc/articles/PMC3716754/ /pubmed/23894719 http://dx.doi.org/10.4161/onci.24572 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Schürch, Christian M
Riether, Carsten
Ochsenbein, Adrian F
Interferons in hematopoiesis and leukemia
title Interferons in hematopoiesis and leukemia
title_full Interferons in hematopoiesis and leukemia
title_fullStr Interferons in hematopoiesis and leukemia
title_full_unstemmed Interferons in hematopoiesis and leukemia
title_short Interferons in hematopoiesis and leukemia
title_sort interferons in hematopoiesis and leukemia
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716754/
https://www.ncbi.nlm.nih.gov/pubmed/23894719
http://dx.doi.org/10.4161/onci.24572
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