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HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients
Regulatory T cells (Tregs) play an important role in controlling antitumor T-cell responses and hence represent a considerable obstacle for cancer immunotherapy. The abundance of specific Treg populations in cancer patients has been poorly analyzed so far. Here, we demonstrate that in breast cancer...
Autores principales: | Schmidt, Hans-Henning, Ge, Yingzi, Hartmann, Felix J, Conrad, Heinke, Klug, Felix, Nittel, Sina, Bernhard, Helga, Domschke, Christoph, Schuetz, Florian, Sohn, Christof, Beckhove, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716760/ https://www.ncbi.nlm.nih.gov/pubmed/23894725 http://dx.doi.org/10.4161/onci.24962 |
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