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Interaction between Trehalose and MTHase from Sulfolobus solfataricus Studied by Theoretical Computation and Site-Directed Mutagenesis
Maltooligosyltrehalose trehalohydrolase (MTHase) catalyzes the release of trehalose by cleaving the α-1,4-glucosidic linkage next to the α-1,1-linked terminal disaccharide of maltooligosyltrehalose. Computer simulation using the hydrogen bond analysis, free energy decomposition, and computational al...
Autores principales: | Fu, Chien-wei, Wang, Yu-Ping, Fang, Tsuei-Yun, Lin, Thy-Hou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716775/ https://www.ncbi.nlm.nih.gov/pubmed/23894317 http://dx.doi.org/10.1371/journal.pone.0068565 |
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