Combined effects of 17-DMAG and TNF on cells through a mechanism related to the NF-kappaB pathway

OBJECTIVE: The tumor necrosis factor (TNF) and the cellular NF-κB pathway protein IKKβ play important roles in various cellular processes such as cell proliferation, survival, differentiation, and apoptosis. A heat shock protein 90 inhibitor, 17-DMAG, can induce apoptosis of some tumor cells. This s...

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Detalles Bibliográficos
Autores principales: Qu, Zhuling, Dong, He, Xu, Xiaolin, Feng, Wei, Yi, Xuanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716826/
https://www.ncbi.nlm.nih.gov/pubmed/23635099
http://dx.doi.org/10.1186/1746-1596-8-70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716826/
https://www.ncbi.nlm.nih.gov/pubmed/23635099
http://dx.doi.org/10.1186/1746-1596-8-70

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