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Combined effects of 17-DMAG and TNF on cells through a mechanism related to the NF-kappaB pathway
OBJECTIVE: The tumor necrosis factor (TNF) and the cellular NF-κB pathway protein IKKβ play important roles in various cellular processes such as cell proliferation, survival, differentiation, and apoptosis. A heat shock protein 90 inhibitor, 17-DMAG, can induce apoptosis of some tumor cells. This s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716826/ https://www.ncbi.nlm.nih.gov/pubmed/23635099 http://dx.doi.org/10.1186/1746-1596-8-70 |