Interleukin-16 Promotes Cardiac Fibrosis and Myocardial Stiffening in Heart Failure with Preserved Ejection Fraction

BACKGROUND: Chronic heart failure (CHF) with preserved left ventricular (LV) ejection fraction (HFpEF) is observed in half of all patients with CHF and carries the same poor prognosis as CHF with reduced LV ejection fraction (HFrEF). In contrast to HFrEF, there is no established therapy for HFpEF. C...

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Detalles Bibliográficos
Autores principales: Tamaki, Shunsuke, Mano, Toshiaki, Sakata, Yasushi, Ohtani, Tomohito, Takeda, Yasuharu, Kamimura, Daisuke, Omori, Yosuke, Tsukamoto, Yasumasa, Ikeya, Yukitoshi, Kawai, Mari, Kumanogoh, Atsushi, Hagihara, Keisuke, Ishii, Ryohei, Higashimori, Mitsuru, Kaneko, Makoto, Hasuwa, Hidetoshi, Miwa, Takeshi, Yamamoto, Kazuhiro, Komuro, Issei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716890/
https://www.ncbi.nlm.nih.gov/pubmed/23894370
http://dx.doi.org/10.1371/journal.pone.0068893

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