Synchronous appendiceal and intramucosal gastric signet ring cell carcinomas in an individual with CDH1-associated hereditary diffuse gastric carcinoma: a case report of a novel association and review of the literature

BACKGROUND: Hereditary diffuse gastric carcinoma is an autosomal dominant cancer syndrome associated with mutations of the E-cadherin gene (CDH1). E-cadherin is normally involved in cell-cell adhesion, so it not surprising that individuals with this syndrome are predisposed to develop malignancies w...

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Detalles Bibliográficos
Autores principales: Hamilton, Leslie E, Jones, Kirsten, Church, Neal, Medlicott, Shaun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716915/
https://www.ncbi.nlm.nih.gov/pubmed/23849133
http://dx.doi.org/10.1186/1471-230X-13-114

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