Resveratrol, a sirtuin 1 activator, increases IL-6 production by peripheral blood mononuclear cells of patients with knee osteoarthritis

BACKGROUND: Sirtuin 1 (Sirt1) is a nuclear enzyme from the class III histone deacetylases that modulates gene expression and is involved in bone and cartilage remodeling. The goal of our study was to evaluate Sirt1 activity in peripheral blood mononuclear cells in patients with osteoarthritis in com...

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Detalles Bibliográficos
Autores principales: Wendling, Daniel, Abbas, Wasim, Godfrin-Valnet, Marie, Guillot, Xavier, Khan, Kashif Aziz, Cedoz, Jean-Pierre, Baud, Lucile, Prati, Clément, Herbein, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716931/
https://www.ncbi.nlm.nih.gov/pubmed/23844973
http://dx.doi.org/10.1186/1868-7083-5-10

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