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Brain H2A.Z: the long and the short

The role of histone variants and their specific post-translational modifications (PTMs) in the epigenetic regulation of gene expression is still poorly understood. A paper published by Simonet and colleagues in Epigenetics and Chromatin describes a new H2A.Z subtype that is specific for brain and pi...

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Detalles Bibliográficos
Autor principal: Ausió, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716961/
https://www.ncbi.nlm.nih.gov/pubmed/23866047
http://dx.doi.org/10.1186/1741-7007-11-84
Descripción
Sumario:The role of histone variants and their specific post-translational modifications (PTMs) in the epigenetic regulation of gene expression is still poorly understood. A paper published by Simonet and colleagues in Epigenetics and Chromatin describes a new H2A.Z subtype that is specific for brain and pituitary in the carp and provides additional information about the functional epigenetic complexity of the PTMs associated with histone H2A.Z. See research article: http://www.epigeneticsandchromatin.com/content/6/1/22