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Let-7b expression determines response to chemotherapy through the regulation of Cyclin D1 in Glioblastoma

BACKGROUND: Glioblastoma is the most common type of primary brain tumors. Cisplatin is a commonly used chemotherapeutic agent for Glioblastoma patients. Despite a consistent rate of initial responses, cisplatin treatment often develops chemoresistance, leading to therapeutic failure. Cellular resist...

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Detalles Bibliográficos
Autores principales:	Guo, Yong, Yan, Kuipo, Fang, Jiasheng, Qu, Qiang, Zhou, Ming, Chen, Fenghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716992/ https://www.ncbi.nlm.nih.gov/pubmed/23806108 http://dx.doi.org/10.1186/1756-9966-32-41

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