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Establishment of patient-derived non-small cell lung cancer xenograft models with genetic aberrations within EGFR, KRAS and FGFR1: useful tools for preclinical studies of targeted therapies

BACKGROUND: Patient-derived tumor xenograft models have been established and increasingly used for preclinical studies of targeted therapies in recent years. However, patient-derived non-small cell lung cancer (NSCLC) xenograft mouse models are relatively few in number and are limited in their degre...

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Detalles Bibliográficos
Autores principales: Zhang, Xu-chao, Zhang, Jingchuan, Li, Ming, Huang, Xiao-sui, Yang, Xue-ning, Zhong, Wen-zhao, Xie, Liang, Zhang, Lin, Zhou, Minhua, Gavine, Paul, Su, Xinying, Zheng, Li, Zhu, Guanshan, Zhan, Ping, Ji, Qunsheng, Wu, Yi-long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716998/
https://www.ncbi.nlm.nih.gov/pubmed/23842453
http://dx.doi.org/10.1186/1479-5876-11-168