Cargando…

Increased invasion and tumorigenicity capacity of CD44(+)/CD24(-) breast cancer MCF7 cells in vitro and in nude mice

BACKGROUND: Identification of cancer stem cells (CSCs) and their behaviors will provide insightful information for the future control of human cancers. This study investigated CD44 and CD24 cell surface markers as breast cancer CSC markers in vitro and in vivo. METHODS: Flow cytometry with CD44 and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Wenxing, Chen, Yubing, Yao, Yueliang, Zhang, Hongmei, Wang, Tiejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717045/ https://www.ncbi.nlm.nih.gov/pubmed/23799994 http://dx.doi.org/10.1186/1475-2867-13-62

Ejemplares similares

Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44(high)/cd24(low )population which is invasive and resistant to anoikis
por: Gauger, Kelly J, et al.
Publicado: (2009)

Tumorigenic and Metastatic Role of CD44(−/low)/CD24(−/low) Cells in Luminal Breast Cancer
por: Vikram, Rajeev, et al.
Publicado: (2020)

Silencing of microRNA-135b inhibits invasion, migration, and stemness of CD24(+)CD44(+) pancreatic cancer stem cells through JADE-1-dependent AKT/mTOR pathway
por: Zhou, Jingyang, et al.
Publicado: (2020)

SWAP-70 promotes glioblastoma cellular migration and invasion by regulating the expression of CD44s
por: Shi, Lin, et al.
Publicado: (2019)

Nicotine reduces effectiveness of doxorubicin chemotherapy and promotes CD44(+)CD24(−) cancer stem cells in MCF-7 cell populations
por: Türker Şener, Leyla, et al.
Publicado: (2018)

RUNX2 interacts with BRG1 to target CD44 for promoting invasion and migration of colorectal cancer cells
por: Yan, Xiaodong, et al.
Publicado: (2020)

Effect of bFGF on the MCF-7 Cell Cycle with CD44(+)/CD24(-): Promoting the G0/G1→G2/S Transition
por: Yang, Zhen-lin, et al.
Publicado: (2012)

Whole-genome approach implicates CD44 in cellular resistance to carboplatin
por: Shukla, Sunita J, et al.
Publicado: (2009)

Staurosporine Induced Apoptosis May Activate Cancer Stem-Like Cells (CD44(+)/CD24(-)) in MCF-7 by Upregulating Mucin1 and EpCAM
por: Zhou, Na, et al.
Publicado: (2015)

Prognostic value of CD44 expression in patients with hepatocellular carcinoma: meta-analysis
por: Luo, Yangkun, et al.
Publicado: (2016)

Koenimbin, a natural dietary compound of Murraya koenigii (L) Spreng: inhibition of MCF7 breast cancer cells and targeting of derived MCF7 breast cancer stem cells (CD44(+)/CD24(−/low)): an in vitro study
por: Ahmadipour, Fatemeh, et al.
Publicado: (2015)

Dynamic regulation of CD24 and the invasive, CD44(pos)CD24(neg )phenotype in breast cancer cell lines
por: Meyer, Matthew J, et al.
Publicado: (2009)

CD44 targets Wnt/β-catenin pathway to mediate the proliferation of K562 cells
por: Chang, Guoqiang, et al.
Publicado: (2013)

hnRNPK promotes gastric tumorigenesis through regulating CD44E alternative splicing
por: Peng, Wei-zhao, et al.
Publicado: (2019)

CD44 cross-linking increases malignancy of breast cancer via upregulation of p-Moesin
por: Hu, Song, et al.
Publicado: (2020)

The role of a new CD44st in increasing the invasion capability of the human breast cancer cell line MCF-7
por: Fang, Xin Jian, et al.
Publicado: (2011)

Downregulation of CD44 reduces doxorubicin resistance of CD44(+)CD24(−) breast cancer cells
por: Van Phuc, Pham, et al.
Publicado: (2011)

The prognostic role of the cancer stem cell marker CD44 in ovarian cancer: a meta-analysis
por: Lin, Jiaying, et al.
Publicado: (2017)

Comparison of the Toxicological Effects of Pesticides in Non-Tumorigenic MCF-12A and Tumorigenic MCF-7 Human Breast Cells
por: Coppola, Lucia, et al.
Publicado: (2022)

Nuclear β-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells
por: Uchino, Masahiro, et al.
Publicado: (2010)

Overexpression of CBS/H(2)S inhibits proliferation and metastasis of colon cancer cells through downregulation of CD44
por: Zhang, Yuyang, et al.
Publicado: (2022)

Unique CD44 intronic SNP is associated with tumor grade in breast cancer: a case control study and in silico analysis
por: Esmaeili, Rezvan, et al.
Publicado: (2018)

Juglone and KPT6566 Suppress the Tumorigenic Potential of CD44(+)CD133(+) Tumor-Initiating Caco-2 Cells In Vitro and In Vivo
por: Kim, Junghoon, et al.
Publicado: (2022)

Isoform switch of CD44 induces different chemotactic and tumorigenic ability in gallbladder cancer
por: Miwa, Takeshi, et al.
Publicado: (2017)

The CD44(+)/CD24(- )phenotype is enriched in basal-like breast tumors
por: Honeth, Gabriella, et al.
Publicado: (2008)

CD24 expression and stem-associated features define tumor cell heterogeneity and tumorigenic capacities in a model of carcinogenesis
por: Ortiz-Montero, Paola, et al.
Publicado: (2018)

CD24 cross-linking induces apoptosis in, and inhibits migration of, MCF-7 breast cancer cells
por: Kim, Jong Bin, et al.
Publicado: (2008)

CD44(+)/CD24(- )breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis
por: Sheridan, Carol, et al.
Publicado: (2006)

CD44, a marker of cancer stem cells, is positively correlated with PD-L1 expression and immune cells infiltration in lung adenocarcinoma
por: Zhang, Chenyue, et al.
Publicado: (2020)

Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF
por: Zhang, Rongsheng, et al.
Publicado: (2019)

Styrylpyrone Derivative (SPD) induces apoptosis in a caspase-7-dependent manner in the human breast cancer cell line MCF-7
por: Lee, Alvin Teck Chien, et al.
Publicado: (2003)

The role of CD24 in multiple myeloma tumorigenicity and effects of the microenvironment on its expression
por: Gilad, Nechama, et al.
Publicado: (2019)

Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity
por: Jaggupilli, Appalaraju, et al.
Publicado: (2012)

CD44/CD24 Expression in recurrent gastric cancer: a retrospective analysis
por: Yong, Ching-Shya, et al.
Publicado: (2012)

CD44/CD24 immunophenotypes on clinicopathologic features of salivary glands malignant neoplasms
por: Soave, Danilo Figueiredo, et al.
Publicado: (2013)

Immunodetection of cells with a CD44+/CD24- phenotype in canine mammary neoplasms
por: Magalhães, Geórgia Modé, et al.
Publicado: (2013)

Cobalt ferrite nanoparticle for the elimination of CD133+CD44(+) and CD44(+)CD24(−), in breast and skin cancer stem cells, using non-ionizing treatments
por: Khalili Najafabad, Bahareh, et al.
Publicado: (2023)

Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan
por: Hiscox, Stephen, et al.
Publicado: (2012)

Can CD44+/CD24- Tumor Cells Be Used to Determine the Extent of Breast Cancer Invasion Following Neoadjuvant Chemotherapy?
por: Wu, Hong, et al.
Publicado: (2011)

CD44(+)/CD24(-) phenotype contributes to malignant relapse following surgical resection and chemotherapy in patients with invasive ductal carcinoma
por: Lin, Yan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_tkk394egid2u708ug7mg4sbtm2