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Isoform-specific effects of ApoE on neurite outgrowth in Olfactory Epithelium culture

BACKGROUND: The apolipoprotein E4 (apoE4) genotype is a major risk factor for developing late-onset Alzheimer’s disease (AD). Inheritance of apoE4 is also associated with impairments in olfactory function in early stages of AD. In this project we examined the effects of the three common isoforms of...

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Detalles Bibliográficos
Autores principales: Hussain, Aseem, Luong, Minh, Pooley, Apryl, Nathan, Britto P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717083/
https://www.ncbi.nlm.nih.gov/pubmed/23845000
http://dx.doi.org/10.1186/1423-0127-20-49