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Isoform-specific effects of ApoE on neurite outgrowth in Olfactory Epithelium culture
BACKGROUND: The apolipoprotein E4 (apoE4) genotype is a major risk factor for developing late-onset Alzheimer’s disease (AD). Inheritance of apoE4 is also associated with impairments in olfactory function in early stages of AD. In this project we examined the effects of the three common isoforms of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717083/ https://www.ncbi.nlm.nih.gov/pubmed/23845000 http://dx.doi.org/10.1186/1423-0127-20-49 |