Accounting for immunoprecipitation efficiencies in the statistical analysis of ChIP-seq data

BACKGROUND: ImmunoPrecipitation (IP) efficiencies may vary largely between different antibodies and between repeated experiments with the same antibody. These differences have a large impact on the quality of ChIP-seq data: a more efficient experiment will necessarily lead to a higher signal to back...

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Detalles Bibliográficos
Autores principales: Bao, Yanchun, Vinciotti, Veronica, Wit, Ernst, ’t Hoen, Peter AC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717085/
https://www.ncbi.nlm.nih.gov/pubmed/23721376
http://dx.doi.org/10.1186/1471-2105-14-169

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