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Linear combination test for gene set analysis of a continuous phenotype

BACKGROUND: Gene set analysis (GSA) methods test the association of sets of genes with a phenotype in gene expression microarray studies. Many GSA methods have been proposed, especially methods for use with a binary phenotype. Equally, if not more importantly however, is the ability to test the enri...

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Detalles Bibliográficos
Autores principales: Dinu, Irina, Wang, Xiaoming, Kelemen, Linda E, Vatanpour, Shabnam, Pyne, Saumyadipta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717275/
https://www.ncbi.nlm.nih.gov/pubmed/23815123
http://dx.doi.org/10.1186/1471-2105-14-212

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