Neurobehavioral Effects of Levetiracetam in Brain Tumor Related Epilepsy

The neurobehavioral profile of anti-epileptic drugs (AEDs) has been a recurrent research topic in the scientific literature. As pharmacological treatments for epilepsy continue to evolve, there is a general consensus that newer AEDs have less detrimental side effects in comparison to their older cou...

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Detalles Bibliográficos
Autores principales: Bernett, Abigail, Phenis, Richard, Fonkem, Ekokobe, Aceves, Jose, Kirmani, Batool, Cruz-Laureano, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717617/
https://www.ncbi.nlm.nih.gov/pubmed/23885253
http://dx.doi.org/10.3389/fneur.2013.00099
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author Bernett, Abigail
Phenis, Richard
Fonkem, Ekokobe
Aceves, Jose
Kirmani, Batool
Cruz-Laureano, Daniel
author_facet Bernett, Abigail
Phenis, Richard
Fonkem, Ekokobe
Aceves, Jose
Kirmani, Batool
Cruz-Laureano, Daniel
author_sort Bernett, Abigail
collection PubMed
description The neurobehavioral profile of anti-epileptic drugs (AEDs) has been a recurrent research topic in the scientific literature. As pharmacological treatments for epilepsy continue to evolve, there is a general consensus that newer AEDs have less detrimental side effects in comparison to their older counterparts. Among newer AEDs and epilepsy patients, potential risk for neurobehavioral changes has been reported with levetiracetam (LEV). Conversely, limited data exists regarding the manifestation of this symptomatology in a subgroup of epilepsy patients with brain tumors. The current paper reviews the literature regarding the neurobehavioral profile of LEV in brain tumor related epilepsy and suggestions for future research will be discussed.
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spelling pubmed-37176172013-07-24 Neurobehavioral Effects of Levetiracetam in Brain Tumor Related Epilepsy Bernett, Abigail Phenis, Richard Fonkem, Ekokobe Aceves, Jose Kirmani, Batool Cruz-Laureano, Daniel Front Neurol Neuroscience The neurobehavioral profile of anti-epileptic drugs (AEDs) has been a recurrent research topic in the scientific literature. As pharmacological treatments for epilepsy continue to evolve, there is a general consensus that newer AEDs have less detrimental side effects in comparison to their older counterparts. Among newer AEDs and epilepsy patients, potential risk for neurobehavioral changes has been reported with levetiracetam (LEV). Conversely, limited data exists regarding the manifestation of this symptomatology in a subgroup of epilepsy patients with brain tumors. The current paper reviews the literature regarding the neurobehavioral profile of LEV in brain tumor related epilepsy and suggestions for future research will be discussed. Frontiers Media S.A. 2013-07-22 /pmc/articles/PMC3717617/ /pubmed/23885253 http://dx.doi.org/10.3389/fneur.2013.00099 Text en Copyright © 2013 Bernett, Phenis, Fonkem, Aceves, Kirmani and Cruz-Laureano. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Neuroscience
Bernett, Abigail
Phenis, Richard
Fonkem, Ekokobe
Aceves, Jose
Kirmani, Batool
Cruz-Laureano, Daniel
Neurobehavioral Effects of Levetiracetam in Brain Tumor Related Epilepsy
title Neurobehavioral Effects of Levetiracetam in Brain Tumor Related Epilepsy
title_full Neurobehavioral Effects of Levetiracetam in Brain Tumor Related Epilepsy
title_fullStr Neurobehavioral Effects of Levetiracetam in Brain Tumor Related Epilepsy
title_full_unstemmed Neurobehavioral Effects of Levetiracetam in Brain Tumor Related Epilepsy
title_short Neurobehavioral Effects of Levetiracetam in Brain Tumor Related Epilepsy
title_sort neurobehavioral effects of levetiracetam in brain tumor related epilepsy
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717617/
https://www.ncbi.nlm.nih.gov/pubmed/23885253
http://dx.doi.org/10.3389/fneur.2013.00099
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