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Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis

The glycolytic enzyme pyruvate kinase (PK) is required for cancer development, and has been implicated in the metabolic transition from oxidative to fermentative metabolism, the Warburg effect. However, the global metabolic response that follows changes in PK activity is not yet fully understood. Us...

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Detalles Bibliográficos
Autores principales:	Bluemlein, Katharina, Glückmann, Matthias, Grüning, Nana-Maria, Feichtinger, René, Krüger, Antje, Wamelink, Mirjam, Lehrach, Hans, Tate, Stephen, Neureiter, Daniel, Kofler, Barbara, Ralser, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2012
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717798/ https://www.ncbi.nlm.nih.gov/pubmed/23154538

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