Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity

Glioblastoma multiforme (GBM) is the most aggressive brain cancer, and to date, no curative treatment has been developed. In this study, we report that miR-211, a microRNA predicted to target MMP-9, is suppressed in grade IV GBM specimens. Furthermore, we found that miR-211 suppression in GBM involv...

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Detalles Bibliográficos
Autores principales: Asuthkar, Swapna, Velpula, Kiran Kumar, Chetty, Chandramu, Gorantla, Bharathi, Rao, Jasti S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717804/
https://www.ncbi.nlm.nih.gov/pubmed/23183822

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