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Blockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-β1/Smad Pathway in Diabetic Mice

The Ca(2+)-activated K(+) channel KCa3.1 mediates cellular signaling processes associated with dysfunction of vasculature. However, the role of KCa3.1 in diabetic nephropathy is unknown. We sought to assess whether KCa3.1 mediates the development of renal fibrosis in two animal models of diabetic ne...

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Detalles Bibliográficos
Autores principales:	Huang, Chunling, Shen, Sylvie, Ma, Qing, Chen, Jason, Gill, Anthony, Pollock, Carol A., Chen, Xin-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717839/ https://www.ncbi.nlm.nih.gov/pubmed/23656889 http://dx.doi.org/10.2337/db13-0135

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