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Npas4 Is a Novel Activity–Regulated Cytoprotective Factor in Pancreatic β-Cells
Cellular homeostasis requires intrinsic sensing mechanisms to temper function in the face of prolonged activity. In the pancreatic β-cell, glucose is likely a physiological trigger that activates an adaptive response to stimulation, thereby maintaining cellular homeostasis. Immediate early genes (IE...
Autores principales: | Sabatini, Paul V., Krentz, Nicole A.J., Zarrouki, Bader, Westwell-Roper, Clara Y., Nian, Cuilan, Uy, Ryan A., Shapiro, A.M. James, Poitout, Vincent, Lynn, Francis C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717850/ https://www.ncbi.nlm.nih.gov/pubmed/23656887 http://dx.doi.org/10.2337/db12-1527 |
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