Evidence for Rapamycin Toxicity in Pancreatic β-Cells and a Review of the Underlying Molecular Mechanisms

Rapamycin is used frequently in both transplantation and oncology. Although historically thought to have little diabetogenic effect, there is growing evidence of β-cell toxicity. This Review draws evidence for rapamycin toxicity from clinical studies of islet and renal transplantation, and of rapamy...

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Detalles Bibliográficos
Autores principales: Barlow, Adam D., Nicholson, Michael L., Herbert, Terry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Methodology Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717855/
https://www.ncbi.nlm.nih.gov/pubmed/23881200
http://dx.doi.org/10.2337/db13-0106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717855/
https://www.ncbi.nlm.nih.gov/pubmed/23881200
http://dx.doi.org/10.2337/db13-0106

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